Two attackers opened fire at a cosmopolitan shooting complex in Tel Aviv, near the Defense Ministry, killing four people and injured another 16.
The assailants, identified as Palestinians, entered a café in Sarona Market and ordered food, but shortly afterwards pulled guns out of their bags and opened fire on unsuspecting crowd inside the café, and then went outside on the spree.
The wounded were admitted to Tel Aviv's central Ichilov Hospital, and are now in stable condition. They were also given emergency treatment at the scene by paramedics.
"When I arrived at the scene I saw two young people who were suffering from gunshot wounds outside of a restaurant at the Sarona center. We treated them as well as numerous other individuals who were suffering from shock," Davidi Dahan, a medic with United Hatzalah, told The Times of Israel.
"While we were treating them other volunteers from the ambucycle unit of United Hatzalah reported that they were treating an unconscious woman behind the Sarona center and that she was in critical condition. We are currently searching for and treating other people who are suffering from shock and who have fed to nearby streets due to the incident," he added.
One eye witness who identified herself as Annette told Israel's Channel 10 television: "I was with the family, eating pizza. We heard the shots, we didn't know what was happening, and everybody got down on the floor. We managed to escape to a cellar."
One of the terrorists was shot by the police, and is being treated with other injured people in the same hospital. The other shooter was captured by the police and is being interrogated.
Hamas, tweeted a picture of the shot militant, with a caption: "One of the heroes of the Tel Aviv operation," but did not claim responsibility for the attack.
In the aftermath of the attack, Israel revoked all Palestinian permits to enter Israel and travel abroad during Muslim holy month of Ramadan.
Israeli Prime Minister Benjamin Netanyahu called the attacks "cold blooded murder by despicable terrorists."
"We will take the necessary steps to attack the attackers and defend those who need to be defended," he told reporters.
"Yata, the village from which the terrorists came, needs to undergo an operation to root out terror. The village needs to be reminded of its history, which already has experience with terrorism," said Transportation Minister and Security Council member Yisrael Katz.
U.S. State Department deputy spokesman Mark Toner condemned the incidence.
"We extend our deepest condolences to the families of those killed and our hopes for a quick recovery for those wounded. These cowardly attacks against innocent civilians can never be justified," he said. "We are in touch with Israeli authorities to express our support and concern."
